? Targeted reaction tank design and model selection of shearing and emulsifying equipment to meet the needs of laboratory scale to production scale.
? Non-standard customized aeration device to reduce the residual of organic solvent and to ensure the solidification of microspheres.
? Excellent pipeline drop design and filter selection to reduce the residue of liquid medicine.
? The design compliments ratio of mixing oil and water to ensure the emulsification effect.
? The selection design of the screening machine ensures the uniformity and reproducibility of the evaluation indexes of the particle size distribution of microspheres.
? Provide different microsphere preparation methods, adapt todifferent APIs, and ensure the encapsulation rate and drug loading.
? The matching isolator system ensures the sterile environment ofthe preparation process.
? Reasonable distribution of Mixing tank and emulsifying tank, filter selection and gradient design, to minimize the residual of liquidmedicine.
? Non-standard customized aeration device can effectively reduceorganic solvent residues.
? Liposome debris collection device to ensure the effective implementation of the back-end process.
? Excellent selection and use of shearing equipment and homogeneous emulsification equipment to effectively ensure particle sizedistribution.
? The key parameters can be controlled to ensure there producibility of the preparation process.
? The design compliments mixing of oil and water to ensure the emulsification effect.
? Inverted tank shearing / homogenizing toensure the complete dispersion and shearing of the liquid medicine. Minor difference of each batch to ensure uniformity and repeatability.
? Effective nitrogen protection ensures product quality and safety.
? Reasonable use of feed isolator and α / βvalve to ensure the sterility and personnel protection of API feeding process.
? Reasonable division of auxiliary material preparation tank area, filter selection and gradient design to minimize there sidual of liquid medicine.
? The high-speed mixing design of the mixing tank makes sure the uniformity of the drug solution before the ball milling /homogenizing, and ensures the ball milling / homogenization effect.
? The special-shaped design of the tank body guarantees the lowest mixing liquid volume.
? Circulating ball milling / homogenizing and rear-end filter network design to ensure the uniformity of the finalparticle size distribution.
? The circular filling design of the buffer tank avoids the riskof suspension subsidence during the suspension filling process.